Select Publications

  • Landin Malt A., Clancy S., Hwang D., Liu A., Smith C., Smith M., Hatley M., Clemens C., Lu X., Non-Canonical Wnt Signaling Regulates Cochlear Outgrowth and Planar Cell Polarity via Gsk3beta Inhibition, 2021; Front Cell Dev Biol. 9() 649830. PMCID: PMC8086559
  • Landin Malt A., Hogan A. K., Smith C. D., Madani M. S., Lu X., Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling, 2020; J Cell Biol. 219(10) . PMCID: PMC7659710
  • Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells., 2019; Proceedings of the National Academy of Sciences of the United States of America. 116(11) 4999-5008. PMCID: PMC6421412
  • Tarchini B, Lu X, New insights into regulation and function of planar polarity in the inner ear., 2019; Neuroscience letters. 709() 134373. PMCID: PMC6732021
  • Goodyear RJ, Lu X, Deans MR, Richardson GP, A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane., 2017; Development (Cambridge, England). 144(21) 3978-3989. PMCID: PMC5702074
  • Xu B, Washington AM, Domeniconi RF, Ferreira Souza AC, Lu X, Sutherland A, Hinton BT, Protein tyrosine kinase 7 is essential for tubular morphogenesis of the Wolffian duct., 2016; Developmental biology. 412(2) 219-33. PMCID: PMC4826835
  • Lu X, Sipe CW, Developmental regulation of planar cell polarity and hair-bundle morphogenesis in auditory hair cells: lessons from human and mouse genetics., 2015; Wiley interdisciplinary reviews. Developmental biology. 5(1) 85-101. PMCID: PMC4552040
  • Andreeva A, Lee J, Lohia M, Wu X, Macara IG, Lu X, PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity., 2014; Developmental cell. 29(1) 20-33. PMCID: PMC4086913
  • Williams M, Yen W, Lu X, Sutherland A, Distinct apical and basolateral mechanisms drive planar cell polarity-dependent convergent extension of the mouse neural plate., 2014; Developmental cell. 29(1) 34-46. PMCID: PMC4120093
  • Sipe CW, Liu L, Lee J, Grimsley-Myers C, Lu X, Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization., 2013; Development (Cambridge, England). 140(8) 1785-95. PMCID: PMC3621493
  • Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium., 2012; Current biology : CB. 22(11) 956-66. PMCID: PMC3407606
  • Sipe CW, Lu X, Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms., 2011; Development (Cambridge, England). 138(16) 3441-9. PMCID: PMC3143564
  • Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis., 2011; Developmental biology. 362(2) 172-86. PMCID: PMC3267834
  • Paudyal A, Damrau C, Patterson VL, Ermakov A, Formstone C, Lalanne Z, Wells S, Lu X, Norris DP, Dean CH, Henderson DJ, Murdoch JN, The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear., 2010; BMC developmental biology. 10() 87. PMCID: PMC2930600
  • Grimsley-Myers CM, Sipe CW, Géléoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis., 2009; The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(50) 15859-69. PMCID: PMC2847287
  • Yen WW, Williams M, Periasamy A, Conaway M, Burdsal C, Keller R, Lu X, Sutherland A, PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation., 2009; Development (Cambridge, England). 136(12) 2039-48. PMCID: PMC2685725